People spend most of their time indoors, thus exposure to indoor pollutants may significantly contribute to cumulative/integrated exposures. Pollutant concentrations in indoor micro-environments are heavily influenced by the individual time activity patterns and by thermal convenience factors, such as the air exchange rate, temperature and humidity. Moreover, exposure airborne pollutants indoors is also affected to a large extent by cultural/societal factors such as the building code, furnishing materials, frequency of tobacco smoking, use of heating, ventilation and air conditioning (HEVAC) systems, application of indoor pesticides, and use of consumer products and of detergents. For example, the Israeli population may experience unique exposures to volatile and semivolatile pollutants that emanate from furniture, charbroiling, and floor sweeping, and to increased pollutant concentrations in indoor environments due to the common hermetic energy saving building code and ventilation preferences. Moreover, dust resuspension in indoor settings is common in many places in Israel.
Current research projects under this theme study the indoor dynamics of different tobacco smoke constituents, in particular nicotine and its progenies (SVOCs), and their chemical effects on molecular and enzymatic changes in saliva.