Exposure estimates were produced for the patients that participate in this study using 3 versions of the ODM model described in (2), including the model that includes the error correction scheme. Medical data were extracted from the Israel National Security Service. Hazard ratios were calculated for different time intervals during the pregnancy period as well as for controlled periods before and after it. Preliminary results suggested that some refining of the epidemiological model is required, including examining additional confounders and possiblt further improving the exposure estimation. These issues are currently discussed among the partners. The work is led by Dr. Raz.